Recent advances in targeted endoscopic imaging: Early detection of gastrointestinal neoplasms

Figure 3 Imaging of vascular endothelial growth factor in the biopsy specimen of human colorectal adenocarcinoma. A: Nonspecific nuclear and cellular staining using acriflavine; B: VEGF-specific staining using AF488-labeled antibodies. The antibody accumulates in the cytoplasm of the tumor cells, but not the nuclei. Reproduced with permission from Foersch et al[39].