Recent advances in the diagnosis and treatment of primary biliary cholangitis

Figure 4 Histology of primary sclerosing cholangitis. Trichrome × 40, liver biopsy. Low power view demonstrating a focal lesion typical for primary sclerosing cholangitis. Periductular layered fibrosis (featuring “onion skin” pattern) is found with edema and inflammation around the interlobular bile ducts in the center of the field[9].