Recent advances in the diagnosis and treatment of primary biliary cholangitis

Figure 2 Histology (hematoxylin and eosin staining) and immunochemical staining of primary biliary cholangitis. A: Magnification × 400; B: Magnification × 400; C, D: Magnification × 400 (left); Magnification × 200 (right). PBC livers demonstrated observably stronger portal area immunostain for CD11c, the position of CD11c sedimentation scored on a 0-4 scale to be compared among PBC, AIH and CHB patients (^aP < 0.05, ^bP < 0.01) (A); PBC hepatic granulomatous lesions were classically situated within portal areas, generally near or around the impaired bile duct (B); Hepatic granulomatous lesions were also occasionally detected in the liver lobule or close to the germinal center (C)[137]. PBC: Primary biliary cholangitis; AIH: Autoimmune hepatitides; CHB: Chronic hepatitis B.