Hepatitis B virus subgenotype F3 reactivation with vaccine escape mutations: A case report and review of the literature

Figure 3 Phylogenetic tree of hepatitis B virus based on complete hepatitis B virus genomes. The tree was constructed using the MEGAv6.0 software package[29], (http//:http://www.megasoftware.net), with the neighbor-joining method with p-distance and 1000 bootstrap replicates. Bootstrap values of at least 70 are shown at the nodes. Phylogenetic analysis was performed using reference sequences from GenBank, indicated in the tree by their GenBank accession numbers. Country of virus origin is included for all genotype F sequences. Woolly monkey HBV was used as the outgroup. The sequence from the patient described in this study is presented in red. HBV: Hepatitis B virus.