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©2014 Baishideng Publishing Group Co.
World J Stem Cells. Apr 26, 2014; 6(2): 82-93
Published online Apr 26, 2014. doi: 10.4252/wjsc.v6.i2.82
Published online Apr 26, 2014. doi: 10.4252/wjsc.v6.i2.82
Figure 2 Intramuscular administration of mesenchymal stem cells mediates a paracrine mechanism of distal organ repair.
The paracrine cascade initiated by mesenchymal stem cells (MSCs) is illustrated by blue arrows. TLR3 priming by poly (I:C) generates a super MSC phenotype through amplification of paracrine factors, which enhances MSC potency for cardiac repair (indicated by triple green plus signs). Supporting data have been published[6,30,31,45,126].
- Citation: Mastri M, Lin H, Lee T. Enhancing the efficacy of mesenchymal stem cell therapy. World J Stem Cells 2014; 6(2): 82-93
- URL: https://www.wjgnet.com/1948-0210/full/v6/i2/82.htm
- DOI: https://dx.doi.org/10.4252/wjsc.v6.i2.82