Unmodified autologous stem cells at point of care for chronic myocardial infarction

Figure 8 Change in cardiac function after delivery of UA-ADRCs or saline. The panels show group-specific mean ± SE of (A) left ventricular ejection fraction (LVEF, (B) cardiac output (CO), (C) stroke volume (SV), (D) end-diastolic volume (EDV), (E) end-systolic volume (ESV) and (F) heart rate (HR) of animals in group 1 (delivery of UA-ADRCs) (green bars) and group 2 (delivery of saline as control) (red bars) at 4 wk after infarction (T1) and 6 wk later (T2). P values of repeated measures two-way analysis of variance are provided in Table 1; results of group-specific Bonferroni's multiple comparison tests are indicated (^aP < 0.05; ^bP < 0.01; ^cP < 0.001). 95% confidence intervals (Bonferroni) of the differences of group-specific mean data between T2 and T1 are shown in (G-L). UA-ADRCs: Fresh, uncultured, unmodified, autologous adipose-derived regenerative cells.