Liquid biopsy for gastric cancer: Techniques, applications, and future directions

Figure 5 CellSearch^® platform. The system analyzes a 7.5 mL blood sample using a ferrofluidic capture reagent, immunofluorescent reagents, and a magnetic field. The ferrofluid reagent comprises a magnetic core surrounded by a polymer layer coated with EpCAM antibodies to capture circulating tumor cells. Fluorescent reagents (CK-PE, DAPI, and anti-CD45) are added, and the sample is loaded into a cartridge within a strong magnetic field. The platform scans the surface of the cartridge, acquires images, and presents them in a gallery format for final classification. Citation: The authors have obtained permission to use the figure from BioRender.com (Supplementary material)[210].