Clinical-radiomics nomogram for predicting esophagogastric variceal bleeding risk noninvasively in patients with cirrhosis

Figure 2 Workflow of the radiomics analysis. A: The liver and spleen regions of interest were defined at the level of the hepatic hilum and the splenic hilum, respectively; B: The least absolute shrinkage and selection operator regression analysis for dimension reduction of radiomics features, and the optimal model parameter λ was selected by 10-fold cross-validation; C: The boxplots of radiomics signatures (RadScore) in the training and validation groups display notable differences respectively. EGVB: Esophagogastric variceal bleeding; nEGVB: Without the occurrence of esophagogastric variceal bleeding.