Advances in the imaging of gastroenteropancreatic neuroendocrine neoplasms

Figure 8 Intravoxel incoherent motion diffusion-weighted imaging in a 67-year-old man with grade 3 pancreatic neuroendocrine neoplasm. A: Axial diffusion weighted image (b = 200 s/mm²) with circular region of interest in the tumor; B: Color-coded diffusion map shows true diffusion coefficient, D = 0.84 × 10³ mm²/s; C: Color-coded perfusion map shows pseudodiffusion coefficient, D* = 5.01 × 10³ mm²/s); D: Color-coded perfusion fraction map shows a value, f = 4.5%; E: Signal decay curve shows steeper decay at low b values and continued fall at higher b values [in comparison to grade 1 pancreatic neuroendocrine neoplasm (PNEN) (Figure 7), true diffusion coefficient is lower in grade 3 PNENs].