Copyright
©The Author(s) 2021.
World J Gastroenterol. Oct 14, 2021; 27(38): 6387-6398
Published online Oct 14, 2021. doi: 10.3748/wjg.v27.i38.6387
Published online Oct 14, 2021. doi: 10.3748/wjg.v27.i38.6387
Figure 4 Mechanism of reactive oxygen species-dependent downregulation of specificity protein transcription factors.
Induction of reactive oxygen species results in epigenetic suppression of Myc, downregulation of microRNAs, induction of ZBTB suppressors and decreased expression of specificity protein (Sp) transcription factors and Sp-regulated genes[20]. ROS: Reactive oxygen species; Sp: Specificity protein.
- Citation: Safe S, Shrestha R, Mohankumar K, Howard M, Hedrick E, Abdelrahim M. Transcription factors specificity protein and nuclear receptor 4A1 in pancreatic cancer. World J Gastroenterol 2021; 27(38): 6387-6398
- URL: https://www.wjgnet.com/1007-9327/full/v27/i38/6387.htm
- DOI: https://dx.doi.org/10.3748/wjg.v27.i38.6387