Fecal microbiota transplantation for irritable bowel syndrome: An intervention for the 21st century

Figure 11  Changes in signals for Alistipes spp. in responders, nonresponders, and placebo groups as well as in the donor. A: Differences in signals for Alistipes spp. between before and 1 mo after transplantation in the responder, nonresponder, and placebo groups; B: There were significant changes in the signals level in responders (P = 0.004). The signal levels also changed in nonresponders, but they did not change in the placebo group. Signal levels at baseline in the responder, nonresponder, and placebo groups as well as the superdonor; C: The baseline signal levels were similar in the responder, nonresponder, and placebo groups, while that for the superdonor was higher. Signal levels in the responder, nonresponder, and placebo groups and the superdonor after transplantation. The signal levels were similar in responders, nonresponders and the superdonor, while it was lower in the placebo group. Citation: El-Salhy M, Hatlebakk JG, Gilja OH, Bråthen Kristoffersen A, Hausken T. Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, double-blind, placebo-controlled study. Gut 2020; 69: 859-867. Copyright @BMJ Publishing Group Ltd 2020. Published by BMJ Publishing Group Ltd[11].