Clinical characteristics and outcomes of patients with hepatic angiomyolipoma: A literature review

Figure 5 Management algorithm for suspected hepatic angiomyolipoma on imaging. ¹Hepatic angiomyolipoma diagnosis is suggested in the presence of fatty tissue within the solid lesion or presence of wash-out. In the presence of tumor-related symptoms, surgical resection is considered first. ²Features suggesting malignant potential are reported in Table 2. Some authors also recommend surgery in the case of epithelioid-type hepatic angiomyolipoma, which would be at greater risk of progression. Likewise, an association with tuberous sclerosis complex is a condition that increases the risk of malignant transformation, by analogy with renal angiomyolipoma[3]. ³Monitoring maintained despite the benign nature of the initial diagnosis because the aggressive behavior of the tumor is difficult to predict. ⁴Other possible therapeutic options include mTOR inhibitors, radiofrequency ablation, arterial embolization in cases of hemorrhagic rupture, and liver transplantation. Citation: Klompenhouwer AJ, Verver D, Janki S, Bramer WM, Doukas M, Dwarkasing RS, de Man RA, IJzermans JNM. Management of hepatic angiomyolipoma: A systematic review. Liver Int 2017; 37(9): 1272-1280. Copyright ©The Author(s) 2017. Published by John Wiley and Sons[3]. MRI: Magnetic resonance imaging; CT: Computed tomography.