Nuclear magnetic resonance-based metabolomics and metabolic pathway networks from patient-matched esophageal carcinoma, adjacent noncancerous tissues and urine

Figure 3 Correlation heat map color-coded by the strength of Spearman correlation coefficients (r) between metabolites found to be important in tumor versus control discrimination. Cut-off values of |r| > 0.4 and P < 0.05 have been used. The metabolites used are those listed in Tables 2 and 3 (metabolites labeled with “*” noted as tissue biomarkers). Red boxes indicate positive associations, and blue boxes indicate negative associations.