Multiomics biomarkers for the prediction of nonalcoholic fatty liver disease severity

Figure 3 Whole interactome of compounds (hexagons), chemical reactions (diamonds), enzymes (squares) and genes (circles) associated with nonalcoholic fatty liver disease. Details on the set of genes and metabolites that were included in the analysis can be found in the main text; terms were filtered according to the ones already found in the databases. The interactome was built using Metscape[73], a plug-in for the widely used network analysis software Cytoscape[74] that supports calculation, analysis and visualization of gene-to-metabolite networks in the context of metabolism.