Post-colonoscopy colorectal cancer rate in the era of high-definition colonoscopy

Figure 3 An early “missed or new” post-colonoscopy colorectal cancer case (No. 7 in Table 2). A 79-year-old man underwent initial colonoscopy, and seven small adenomatous polyps in the ascending and sigmoid colon were resected. A: A diminutive lesion 4 mm in size was found in the sigmoid colon during surveillance colonoscopy 15 mo after initial colonoscopy; B: Chromoendoscopy with indigo-carmine dye visualizes the margin of the deep depressed area on the surface of the lesion, and crystal violet stain shows a type-Vi pit with an invasive pattern suggesting submucosal deep invasive cancer (C); D: Histopathological examination of the surgical specimen reveals well to moderately differentiated adenocarcinoma with submucosal deep (3000 μm) invasion and no lymph node metastasis.