Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review

doi:10.3748/wjg.v22.i29.6742

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 7, 2016; 22(29): 6742-6756
Published online Aug 7, 2016. doi: 10.3748/wjg.v22.i29.6742

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Figure 3 Effects of TM6SF2 genetic variations. TM6SF2 plays a role in VLDL export from liver to serum which results in increased serum lipids and myocardial infarction, and decreased risk of liver steatosis. From Kahali et al[67], used by permission of the copyright holder. Chol: Cholesterol; LDL: Low-density lipoprotein cholesterol; IHTG: Intrahepatic triglyceride; NASH: Nonalcoholic steatohepatitis; TG: Triglyceride; VLDL: Very low-density lipoprotein.

Citation: Severson TJ, Besur S, Bonkovsky HL. Genetic factors that affect nonalcoholic fatty liver disease: A systematic clinical review. World J Gastroenterol 2016; 22(29): 6742-6756
URL: https://www.wjgnet.com/1007-9327/full/v22/i29/6742.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i29.6742