Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression

Figure 2 Effect of fenofibrate (100 mg/kg) and resveratrol (70 mg/kg) alone and in combination (half doses) on OGTT (A), blood glucose (B), insulin (C) and HOMA (D) in fructose-induced NASH in rats. Values are mean ± SE (SE was omitted in Figure 2A OGTT for clarification). n = 8-12 rats.The significance of the difference between means was tested by ANOVA followed by Tukey Kramer multiple comparisons test. ^aP < 0.05 vs control; ^bP < 0.05 vs FED. FED: Fructose enriched diet; FENO: Fenofibrate; RES: Resveratrol; OGTT: Oral glucose tolerance test; HOMA: Homeostasis model of assessment.