Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression

Figure 1 Effect of fenofibrate (100 mg/kg) and resveratrol (70 mg/kg) alone and in combination (half doses) on the body weight (A) and percentage of liver index (B) in fructose-induced NASH in rats. Values are means ± SE (SE was omitted in Figure 1A body weight for clarification). n = 8-12 rats. The significance of the difference between means was tested by ANOVA followed by Tukey Kramer multiple comparisons test. ^aP < 0.05 vs control; ^bP < 0.05 vs FED; ^cP < 0.05 vs FENO; ^dP < 0.05 vs RES. FED: Fructose enriched diet; FENO: Fenofibrate; RES: Resveratrol; Liver index: Liver weight/body weight.