Immunohistochemical expression of SP-NK-1R-EGFR pathway and VDR in colonic inflammation and neoplasia

Figure 3 Expression of phosphorylated epidermal growth factor receptor in colonic tissue. A: Phosphorylated epidermal growth factor receptor (pEGFR) expression in tissue from normal, inflammatory bowel disease (IBD), sporadic dysplasia, sporadic colorectal cancer, and colitis-associated colorectal cancer (CAC) patients (n = 5 patients per group except CAC, where n = 6). ^aP < 0.05 and ^bP < 0.01 vs normal; B: Expression of pEGFR in different diagnostic areas found within tissue from CAC patients. Each patient is identified by a unique symbol (see Table 2). IHC: Immunohistochemistry.