Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma

Figure 3 Common mutations in the HBx gene. Substitution mutations at nucleotide positions T1753C, A1762T, G1764A and T1768A; and C-terminal truncations ranging from nucleotide position 1647 to 1790 observed in human HCC tumor samples[43]. HBx gene nucleotide position 1374 to 1834 as shown in Figure 1.