Endoscopic surveillance of gastric cancers after Helicobacter pylori eradication

Figure 3 Differentiated-type early gastric cancer detected after successful Helicobacter pylori eradication. A: This endoscopic finding made qualitative cancer diagnosis difficult by conventional endoscopy; B: A “gastritis-like” appearance under narrow-band imaging with magnified endoscopy was demonstrated by a microsurface structure comprised of mixed pits and papillae, resembling the surrounding non-cancerous mucosa; C: Well-differentiated tubular adenocarcinoma with low-grade atypia (hematoxylin and eosin staining); D: Ki-67 positive cells localized in the middle-to-lower portion of the mucosa, indicating cytological maturation at the luminal surface layer of the cancer[47].