Campylobacter concisus and inflammatory bowel disease

Figure 2 An example showing that collection of multiple intestinal biopsies increases the detection of intestinal prevalence of Campylobacter concisus. Data included in Figure 2 were from reference 20. In both patients with inflammatory bowel disease (IBD) (right column) and healthy controls (left column), the detection of intestinal prevalence of Campylobacter concisus (C. concisus) was greatly increased using four biopsies as compared to using one biopsy. In healthy controls, C. concisus detection rates in a single biopsy collected from ileum, caecum, colon and rectum were 21%, 18%, 18% and 9% respectively. If results from the four biopsies were used in determining the intestinal prevalence of C. concisus, the intestinal prevalence of C. concisus in healthy controls was 36%. Similarly, in patients with IBD, C. concisus detection rates in a single biopsy collected from ileum, caecum, colon and rectum were 23%, 15%, 43% and 26% respectively, and the intestinal prevalence of C. concisus in patients with IBD was 68% when four biopsies were taken into consideration.