MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential

doi:10.3748/wjg.v20.i38.13658

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Oct 14, 2014 (publication date) through Dec 22, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2014; 20(38): 13658-13666
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13658

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Figure 1 MicroRNAs and their influence on multidrug resistance in gastric cancer. The figure presents an overview about the targets and pathways that mediate the effects of miRNA manipulation on multidrug resistance in gastric cancer (Data modified from DIANA miRPathv2.0[90]). The arrows indicate the up- or down-regulation of miRNA patterns in gastric cancer cells in vitro. The dashed boxes indicate nucleus related targets. Interrogation marks represent to date unknown intermediate steps. STAT: Signal transducers and activators of transcription; mTOR: Mammalian target of rapamycin; PKB: Protein kinase B.

Citation: Matuszcak C, Haier J, Hummel R, Lindner K. MicroRNAs: Promising chemoresistance biomarkers in gastric cancer with diagnostic and therapeutic potential. World J Gastroenterol 2014; 20(38): 13658-13666
URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13658.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i38.13658