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World J Gastroenterol. Oct 14, 2014; 20(38): 13648-13657
Published online Oct 14, 2014. doi: 10.3748/wjg.v20.i38.13648
Figure 1
Figure 1 Principle of matrix-assisted laser desorption-ionization imaging mass spectrometry. A section is cut from frozen tissue and prepared for mass spectrometry by coating with matrix solution. Energy for desorption and ionization is supplied by a pulsed laser beam. For each point in the user-defined measurement grid, a mass spectrum is generated by MALDI-TOF MS[79]. Copyright © 2009, Rights Managed by Nature Publishing Group. MALDI: Matrix-assisted laser desorption-ionization; TOF: Time-of-flight; MS: Mass spectrometry.