Pancreatic enzyme replacement therapy for pancreatic exocrine insufficiency in the 21st century

Figure 4 Effect of increasing the enzyme dosage on fecal fat excretion on a 100 gram fat diet. Enzymes were given 3 times per day with meals providing approximately 30000, 60000, or 120000 USP lipase units with each meal or as 18000 USP lipase units as enteric coated microspheres (i.e., 3 tablets, 6 tablets or 12 tablets and 3 microsphere capsules with each meal). Each rectangle encloses the mean ± the standard deviation of the mean. The normal fecal fat is < 6 g/24 h. From[29] with permission.