Relationship between methylation and colonic inflammation in inflammatory bowel disease

doi:10.3748/wjg.v20.i30.10591

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 20, Issue 30

This Article

Academic Content and Language Evaluation of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (6057)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Tables (1-5) series.

Item

Count

PDF

433

WORD

259

HTML

3289

Tables (1-5)

210

Sum=4191

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

981

Download

863

Sum=1844

Aug 14, 2014 (publication date) through Jan 8, 2025

Times Cited of This Article

Times Cited (10)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Gastroenterol. Aug 14, 2014; 20(30): 10591-10598
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10591

Table 3 Methylation status and disease activity according to disease location

Variable (% samples)	Distal colon	Proximal colon	Pvalue
Endoscopic activity¹	48/101 (48)	21/121 (17)	< 0.001
Active histological activity²	30/97 (31)	16/115 (13)	0.004
Methylation of SLIT²	43/101 (43)	23/121 (19)	< 0.001
Methylation of TGFB²	24/90 (27)	16/117 (14)	0.022

¹Endoscopic activity was defined as Mayo > 0 for ulcerative colitis or Crohn’s disease activity index of severity > 0 for Crohn’s disease;

²Active histological activity was defined as the presence of neutrophils in conjunction with epithelial cell damage.

Citation: Lobatón T, Azuara D, Rodríguez-Moranta F, Loayza C, Sanjuan X, de Oca J, Fernández-Robles A, Guardiola J, Capellá G. Relationship between methylation and colonic inflammation in inflammatory bowel disease. World J Gastroenterol 2014; 20(30): 10591-10598
URL: https://www.wjgnet.com/1007-9327/full/v20/i30/10591.htm
DOI: https://dx.doi.org/10.3748/wjg.v20.i30.10591