Treating inflammatory bowel disease by adsorptive leucocytapheresis: A desire to treat without drugs

Figure 3 Selective depletion of myeloid lineage cells (neutrophils, monocytes and platelets) by adsorptive granulocyte and monocyte apheresis with the Adacolumn in patients with inflammatory bowel disease. In each case, the column inflow count was expressed as 100% and the column outflow count (return to patient) was expressed as a percentage of the inflow count taken 30 min (peak fall) during a 60-min granulocyte and monocyte apheresis (GMA) session. The data serve as a solid basis for the argument that GMA selectively depletes granulocytes, monocytes/macrophages together with a significant fraction of platelets, but spares lymphocytes[22,23,48,117].