CacyBP/SIP nuclear translocation induced by gastrin promotes gastric cancer cell proliferation

Figure 5 Localization of calcyclin binding protein/Siah-1 interacting protein nuclear translocation. A: Immunofluorescent localization of CacyBP/SIP in cultured SGC7901-CacyBP/SIPsi1 cells. a, b and c, unstimulated cells; d, e and f, cells 8 h after gastrin (10^-8 mol/L) stimulation; a and d, immunostained using anti-CacyBP/SIP MAb; b and e, PI stained; c and f, merged images; B: Amounts of CacyBP/SIP in nuclear extracts are shown before and after gastrin (10^-8 mol/L) stimulation. CacyBP/SIP: Calcyclin binding protein/Siah-1 interacting protein; C: Cytosolic markers; N: Nuclear markers.