Association of human leukocyte antigen DQB1 and DRB1 alleles with chronic hepatitis B

Figure 2 Possible model illustrating the single-nucleotide polymorphic regions of major histocompatibility complex class II that affect T-cell receptor recognition. The yellow asterisks show mutational sites that are buried in the peptide-binding pocket, whereas the white asterisks indicate mutations in the solvent-exposed T-cell recognition regions. This model was built according to the available crystal structures, which were published previously[41].