Characteristics and prognosis of gastric cancer in patients aged ≥ 70 years

Table 4 Survival analysis of gastric cancer patients aged ≥ 70 years

Characteristics	n (%)	5-yr OS	MST (mo)	Univariate analysis		Multivariate analysis
				χ2	P (log-rank)	Hazard ratio (95%CI)	P value
Gender				4.009	0.045
Female	58 (21.2)	29.30%	31			1 (ref)
Male	215 (78.8)	20.00%	18			1.433 (1.013, 2.029)	0.042
Age (yr)				0.092	0.762
< 75	164 (60.1)	23.20%	20
≥ 75	109 (39.9)	20.20%	19
Tumor location				6.055	0.109
Lower 1/3	78 (28.6)	25.60%	22
Middle 1/3	58 (21.2)	22.40%	15
Upper 1/3	106 (38.8)	21.70%	22
2/3 or more	31 (11.4)	12.90%	16
Tumor size				8.715	0.003
< 5 cm	87 (31.9)	32.20%	31			1 (ref)
≥ 5 cm	186 (68.1)	17.20%	17			1.119 (0.816, 1.533)	0.485
Borrmann type				3.221	0.073
I/II	95 (34.8)	27.40%	26
III/IV	178 (65.2)	19.10%	18
Histology				5.610	0.018
Differentiated	116 (42.5)	28.40%	23			1 (ref)
Undifferentiated	157 (57.5)	17.20%	18			1.272 (0.956, 1.693)	0.099
Extranodal metastasis				16.966	< 0.001
Negative	223 (81.7)	24.70%	23			1 (ref)
Positive	45 (18.3)	10.00%	11			1.248 (0.873, 1.784)	0.225
Surgical margin status				8.957	0.003
Negative	241 (88.3)	24.10%	22			1 (ref)
Positive	32 (11.7)	6.30%	12			1.583 (1.048, 2.391)	0.029
Depth of invasion				20.751	< 0.001
pT1-T3	45 (16.5)	51.10%	65			1 (ref)
pT4	228 (83.5)	16.20%	17			1.773 (1.118, 2.811)	0.015
Lymph node metastasis				30.397	< 0.001
pN0	87 (31.9)	40.20%	44			1 (ref)
pT1-N3	186 (68.1)	13.40%	16			1.658 (1.178, 2.334)	0.004
Distant metastasis				18.941	< 0.001
M0	264 (96.7)	22.70%	21			2.332 (1.143, 4.756)	0.020
M1	9 (3.3)	0.00%	6
Chemotherapy				0.508	0.476
Yes	36 (13.2)	13.90%	20
No	237 (86.8)	23.20%	20
Type of gastrectomy				11.316	0.001
Subtotal	214 (78.4)	24.80%	22			1 (ref)
Total	59 (21.6)	11.90%	14			1.305 (0.936, 1.820)	0.117
Extent of lymphadenectomy				1.429	0.232
D2	91 (33.3)	19.80%	17
D1	182 (66.7)	23.10%	22

Ref: Reference category; OS: Overall survival; MST: Median survival time.