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World J Gastroenterol. Oct 21, 2013; 19(39): 6568-6578
Published online Oct 21, 2013. doi: 10.3748/wjg.v19.i39.6568
Published online Oct 21, 2013. doi: 10.3748/wjg.v19.i39.6568
Characteristics and prognosis of gastric cancer in patients aged ≥ 70 years
Yue-Xiang Liang, Jing-Yu Deng, Xue-Wei Ding, Xiao-Na Wang, Bao-Gui Wang, Li Zhang, Han Liang, Department of Gastric Cancer, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Tianjin 300060, China
Han-Han Guo, Department of Cardiovascular Surgery, the First Hospital of Tianshui City, Tianshui 741000, Gansu Province, China
Author contributions: Liang YX, Liang H, Deng JY and Guo HH performed the majority of the study; Deng JY, Ding XW, Wang XN, Zhang L and Guo HH designed the study and analyzed data; Liang YX, Liang H, Wang BG and Guo HH wrote the manuscript; Deng JY, Ding XW, Wang BG and Wang XN revised the manuscript.
Supported by National Basic Research Program of China: 973 Program, No. 2010CB529301
Correspondence to: Han Liang, Professor, Department of Gastric Cancer, Tianjin Medical University Cancer Institute and Hospital, Key Laboratory of Cancer Prevention and Therapy, National Clinical Research Center of Cancer, Huanhuxi Road, Hexi District, Tianjin 300060, China. tjlianghan@sohu.com
Telephone: +86-22-23340123 Fax: +86-22-23340123
Received: May 19, 2013
Revised: July 28, 2013
Accepted: August 4, 2013
Published online: October 21, 2013
Revised: July 28, 2013
Accepted: August 4, 2013
Published online: October 21, 2013
Core Tip
Core tip: Few studies have compared the characteristics and prognosis of gastric cancer among younger, middle-aged and elderly patients. Elderly patients have distinctive properties, and we have to treat them individually with particular care. We found that age ≥ 70 years was an independent prognostic factor for patients with gastric cancer after gastrectomy and these patients had distinctive characteristics of male predominance, larger tumor size, more histological differentiation, higher number of tumors located in the upper third of the stomach, and advanced tumor-node-metastasis stage, but less distant metastasis compared to younger and middle-aged patients.