Elevated serum levels of human relaxin-2 in patients with esophageal squamous cell carcinoma

Figure 2 Comparison of overall survival between different disease stages. We also analyzed the prognostic value of human relaxin 2 (H2 RLN) levels in selected patient subgroups stratified according to disease stage. Esophageal squamous cell carcinoma patients with elevated H2 RLN levels had a significantly shorter overall survival rate compared to patients with non-elevated H2 RLN levels in the clinical stage I-II subgroup (n = 54; log-rank P < 0.001; Figure 3A), and the clinical stage III-IV subgroup (n = 87; log-rank P < 0.001; Figure 3B).