Association between gastric cancer and -1993 polymorphism of TBX21 gene

Table 1 Distribution of TBX21 -1993T/C allelic frequencies in cases and controls n (%)

Variables	Case	Control	Adjusted OR (95% CI)	P trend
Age (yr) (mean ± SD)	41.14 ± 7.10	41.69 ± 8.83		0.8841
Gender
Male	124 (56.36)	143 (54.58)		0.6952
Female	96 (43.64)	119 (45.42)
Smoking status
Never	160 (72.73)	201 (76.72)		0.3142
Always	60 (27.27)	61 (23.28)
Drinking status
Never	149 (67.73)	188 (71.76)		0.3372
Always	71 (32.27)	74 (28.24)
Family history of cancer
No	181 (82.27)	240 (91.60)		0.0022
Yes	39 (17.73)	22 (8.40)
TBX21 -1993
T	356 (80.91)	473 (90.27)	1.00	-
C	84 (19.09)	51 (9.73)	2.06 (1.44-2.96)	< 0.0012
T/T	154 (70.00)	219 (83.59)	1.00	-
T/C	48 (21.82)	35 (13.36)	1.84 (1.13-3.01)	0.0153
C/C	18 (8.18)	8 (3.05)	3.42 (1.41-8.31)	0.0073

¹Mann-Whitney U test;

²χ² test;

³Multivariate unconditional logistic regression model. SD: Standard deviation; CI: Confidence interval; OR: Odds ratio.