Non-viral causes of hepatocellular carcinoma

Figure 7 Relative risks of liver cancer associated with coffee consumption (per 2 cups/d increment). Squares represent study-specific relative risk estimates (size of the square reflects the study-specific statistical weight, that is, the inverse of the variance); horizontal lines represent 95% CIs; diamonds represent summary relative risk estimates with corresponding 95% CIs. Tests for heterogeneity: all studies, Q = 11.56, P = 0.17, I² = 30.8%; cohort studies, Q = 1.74, P = 0.63, I² = 0%; case-control studies, Q = 9.28, P = 0.05, I² = 36.9%. Reprinted from Larsson SC, Wolk A. Coffee consumption and risk of liver cancer: a meta-analysis. Gastroenterology 2007; 132: 1740-1745, Copyright (2007), with permission from Elsevier[66].