Pseudomonas exotoxin antisense RNA selectively kills hepatitis B virus infected cells

Figure 4 Cytotoxicity of toxin sense and antisense RNA to DHBV infected duck hepatocytes in the presence or absence of of 10 mmol/L adefovir. 7.5 &mgr;g RNA mixed with 7.5 &mgr;g p92 β-Gal expression plasmid were transfected in each experiment and β-Gal activities were quantified as described in legend to Figure 5. In addition, a wild-type HBV polymerase expression plasmid was transfected (7.5 &mgr;g). P92, control RNA from p92; p77, antisense RNA of inactivated toxin from p77; p95, sense toxin RNA from p95; p100, antisense RNA of active toxin from p100.