Carbon liberated from CO-releasing molecules attenuates leukocyte infiltration in the small intestine of thermally injured mice

Figure 4 Effects of CORM-2 on protein expression of HO-1 in the ileum tissue of thermally injured mice. Mice were challenged with thermal injury and treated with CORM-2 as described in Figure 1. Protein expression of HO-1 was performed by Western blotting 24 h after thermal injury. A representative experiment showed that HO-1 was significantly up-regulated by thermal injury (lane 2). Expression of HO-1 in the small intestine of thermally injured mice treated with CORM-2 was more significantly increased compared to burned mice without CORM-2 (lane 4).