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©2007 Baishideng Publishing Group Inc.
World J Gastroenterol. Dec 7, 2007; 13(45): 5989-5994
Published online Dec 7, 2007. doi: 10.3748/wjg.v13.i45.5989
Published online Dec 7, 2007. doi: 10.3748/wjg.v13.i45.5989
Group | Pre-injection | Post-injection CCl4 | |||||
Post-24 h | Post-2 d | Post-3 d | Post-4 d | Post-7 d | Post-14 d | ||
ALT/(U/L) | |||||||
Control | 26.00 | 1156.00 | 43.50 | 1018.00 | 1790.50 | 1349.50 | 297.00 |
(16.50-33.75) | (245.00-1641.75) | (13.25-4399.75) | (66.00-1970.00) | (1763.00-1818.00) | (1307.00-1392.00) | (244.00-350.00) | |
OAT | 24.50 | 113.00 | 95.00 | 173.00 | 135.00 | 465.00a | 77.50a |
(17.75-26.25) | (26.50-439.00) | (43.50-427.50) | (61.25-918.50) | (52.50-1390.50) | (109.75-875.00) | (16.00-155.50) | |
O3 | 25.50 | 564.00 | 474.00 | 209.00 | 259.00 | 139.00a | 32.00a |
(12.00-37.25) | (75.00-1054.50) | (132.00-1025.50) | (126.50-1136.00) | (119.00-1377.00) | (57.50-538.00) | (25.00-70.00) | |
YC | 18.00 | 1310.00c | 662.00c | 1610.50 | 1064.50 | 465.00a | 77.50a |
(11.75-52.50) | (919.75-1740.25) | (355.00-2034.50) | (158.75-1682.50) | (235.25-2394.00) | (109.75-875.00) | (16.00-155.50) | |
O3 + YC | 26.50 | 28.50fh | 34.00cfh | 33.50adfh | 30.50adfh | 23.50adfg | 12.00adfg |
(20.00-32.75) | (23.50-41.75) | (27.25-40.25) | (27.75-37.75) | (26.50-38.75) | (20.00-36.00) | (3.75-12.50) | |
AST/ALT | |||||||
Control | 0.78 | 1.36 | 5.71 | 0.06 | 0.05 | 0.10 | |
(0.45-1.38) | (0.28-6.94) | (0.13-11.29) | (0.03-0.09) | (0.03-0.07) | (0.09-0.10) | ||
OAT | 0.80 | 0.49 | 0.41 | 0.43 | 0.57 | 0.99a | |
(0.50-2.97) | (0.17-0.85) | (0.18-0.70) | (0.10-0.77) | (0.15-0.79) | (0.29-1.70) | ||
O3 | 1.02 | 0.81 | 0.45 | 0.62 | 0.71a | 1.52a | |
(0.77-1.35) | (0.38-1.36) | (0.15-0.65) | (0.22-0.94) | (0.33-1.05) | (0.75-2.24) | ||
YC | 0.73 | 1.09 | 0.43 | 0.21 | 0.24 | 1.00a | |
(0.48-1.11) | (0.62-7.86) | (0.26-0.78) | (0.07-0.45) | (0.07-0.87) | (0.20-2.02) | ||
O3 + YC | 2.39bfh | 2.08df | 1.09dfh | 1.39adfh | 1.43adfg | 2.08ac | |
(1.56-2.59) | (1.43-2.17) | (1.00-1.70) | (1.26-1.79) | (1.04-1.92) | (1.77-3.79) | ||
TBIL/(μmol/L) | |||||||
Control | 2.10 | 7.15 | 9.80 | 6.65 | 6.10 | 4.95 | 1.80 |
(0.18-4.73) | (2.73-31.83) | (6.15-33.85) | (6.60-6.70) | (5.30-6.90) | (4.70-5.20) | (0.60-3.00) | |
OAT | 3.80 | 5.20 | 5.30 | 6.55 | 3.50a | 5.45 | 3.30 |
(0.85-4.70) | (2.50-6.40) | (1.90-14.30) | (3.35-21.15) | (2.05-4.20) | (1.88-10.90) | (1.20-6.08) | |
O3 | 1.55 | 4.30 | 4.30 | 3.30 | 1.90a | 2.50a | 3.00 |
(0.20-4.85) | (2.45-5.65) | (3.05-7.05) | (1.95-6.45) | (1.10-4.35) | (1.85-4.20) | (0.80-4.95) | |
YC | 2.65 | 3.40 | 7.00 | 3.40a | 4.45 | 1.95a | 2.70 |
(0.35-5.18) | (1.60-26.15) | (2.95-33.65) | (1.15-3.55) | (1.55-5.78) | (0.80-3.93) | (0.98-10.73) | |
O3 + YC | 4.20 | 1.95ace | 1.00bceh | 1.45ac | 1.30adg | 0.85ace | 3.50 |
(3.83-4.33) | (0.10-2.40) | (0.30-2.38) | (0.80-5.10) | (0.70-1.55) | (0.50-2.13) | (0.50-4.28) | |
PT/s | |||||||
Control | 6.80 | 13.20 | 18.90 | 12.25 | 8.70 | 7.80a | 8.55a |
(6.50-13.05) | (8.93-38.93) | (12.40-60.70) | (11.70-12.80) | (8.40-9.00) | (7.60-8.00) | (8.20-8.90) | |
OAT | 6.50 | 7.20a | 7.85a | 7.95 | 6.50 | 6.50 | 6.50 |
(6.50-7.28) | (6.50-8.35) | (7.60-9.83) | (6.50-9.40) | (6.50-8.70) | (6.50-6.50) | (6.95-7.93) | |
O3 | 7.30 | 8.60 | 9.50 | 7.80a | 7.30 | 7.50 | 7.10a |
(6.95-8.03) | (7.30-11.35) | (8.65-16.35) | (7.50-10.00) | (6.90-8.45) | (7.00-7.70) | (6.80-7.30) | |
YC | 7.70 | 12.55 | 9.90 | 7.40a | 7.20 | 7.55 | 6.90 |
(7.18-8.20) | (8.23-24.75) | (8.70-36.40) | (7.20-10.60) | (6.68-8.70) | (6.68-8.20) | (6.50-8.13) | |
O3 + YC | 7.65 | 7.25acg | 7.40bcfh | 7.30a | 7.30a | 6.85a | 7.45a |
(7.35-8.15) | (6.50-8.13) | (7.20-8.65) | (7.18-8.28) | (7.28-7.40) | (6.50-7.50) | (7.03-7.70) | |
AMMO/(μmol/L) | |||||||
Control | 69.55 | 96.50 | 114.80 | 132.80 | 143.40 | 53.00 | 91.40 |
(35.47-106.35) | (53.20-161.33) | (80.90-133.90) | (82.30-183.30) | (67.40-219.40) | (32.50-73.50) | (40.60-142.20) | |
OAT | 41.20 | 54.70 | 44.35a | 49.85a | 55.10a | 49.65 | 33.30 |
(35.45-54.50) | (43.70-79.70) | (25.93-83.10) | (38.48-62.28) | (31.35-64.53) | (38.55-75.45) | (13.40-52.50) | |
O3 | 49.75 | 54.70 | 51.50a | 65.70a | 48.30 | 65.40 | 47.10 |
(39.33-62.03) | (52.40-76.65) | (43.00-73.50) | (52.20-72.40) | (44.85-74.05) | (44.50-94.80) | (32.63-63.75) | |
YC | 47.50 | 53.80 | 54.70a | 55.70 | 77.35 | 45.40 | 45.50 |
(34.25-73.23) | (49.45-173.23) | (43.70-79.70) | (45.83-86.95) | (57.63-168.25) | (39.18-97.68) | (23.35-110.85) | |
O3 + YC | 63.50 | 77.35 | 55.30a | 59.65a | 58.40 | 67.10 | 41.90 |
(15.60-74.78) | (56.73-158.20) | (44.90-69.58) | (41.70-63.45) | (45.95-69.25) | (51.20-93.95) | (37.08-61.48) | |
BUN/(mmol/L) | |||||||
Control | 3.30 | 5.50 | 3.80 | 2.40 | 3.60 | 3.65 | 5.15 |
(2.45-4.45) | (3.85-7.15) | (2.70-6.20) | (1.60-3.20) | (3.10-4.10) | (3.20-4.10) | (1.20-9.10) | |
OAT | 3.85 | 6.20 | 4.50 | 3.70 | 4.65 | 3.20 | 2.75 |
(3.53-4.38) | (5.20-8.30) | (4.10-6.25) | (3.25-4.60) | (3.10-7.33) | (2.38-6.65) | (2.10-4.00) | |
O3 | 3.75 | 5.70 | 5.80 | 4.00 | 3.90 | 2.60 | 2.60 |
(3.18-5.55) | (4.65-8.70) | (4.75-7.05) | (3.20-5.80) | (2.40-6.45) | (1.90-6.35) | (2.20-3.30) | |
YC | 3.50 | 7.55 | 4.30 | 4.10 | 3.00 | 2.00 | 3.20 |
(2.88-5.73) | (3.90-13.58) | (3.55-13.00) | (1.98-7.13) | (2.55-6.68) | (1.68-6.75) | (2.83-3.20) | |
O3 + YC | 2.85 | 3.10deg | 3.50e | 3.75 | 3.45 | 2.20 | 1.80g |
(2.28-3.65) | (1.50-3.98) | (2.70-4.15) | (2.30-4.68) | (3.30-3.95) | (1.80-3.28) | (1.70-2.40) |
- Citation: Li LJ, Yang YG, Zhang ZL, Nie SF, Li Z, Li F, Hua HY, Hu YJ, Zhang HS, Guo YB. Protective effects of medical ozone combined with traditional Chinese medicine against chemically-induced hepatic injury in dogs. World J Gastroenterol 2007; 13(45): 5989-5994
- URL: https://www.wjgnet.com/1007-9327/full/v13/i45/5989.htm
- DOI: https://dx.doi.org/10.3748/wjg.v13.i45.5989