Role of N-acetylcysteine in rifampicin-induced hepatic injury of young rats

Table 2 Effect of RMP treatment (50 mg/kg/day for 3 wk) and NAC (100 mg/kg/day for 3 wk) on lipid peroxidation, catalase, superoxide dismutase, glutathione-S-transferase(nmol/min/mg protein) in rats (mean±SD)

Group	Lipid peroxidation (nmolMDA/g tissue/10min)	Catalase(µmol/min/mgprotein)	Superoxidedismutase (IU)	Glutathione-S-transferaseusing EA
Control	120.47±9.3	310.32±31.2	17.92±2.25	13.94±2.27
RMP	163.52±22.6b	204.92±28.6b	11.71±1.39b	18.58±1.52Wb
RMP + NAC	138.71±13.2Wa	269.48±19.5Wa	14.38±2.47Wa	15.92±1.38a
NAC	103.59±12.9	317.51±38.7a	16.47±2.80	14.59±2.18

^aP < 0.05 vs control, ^bP < 0.001 vs control.