Urinary nucleosides as biological markers for patients with colorectal cancer

Table 3 Comparison of levels of urinary nucleosides from healthy adults, patients with intestinal villous adenoma and colorectal can-cer (mean±SD, nmoL/µmoL creatinine)

Nucleoside	Healthy adults	Patients with	Patients with
		intestinal villous	colorectal cancer
		adenoma
Pseu	22.08 ± 5.11	23.99 ± 5.61	42.19 ± 22.25a
C	0.15 ± 0.12	0.40 ± 0.21c	0.43 ± 0.49a
U	0.30 ± 0.15	0.31 ± 0.12	0.31 ± 0.23
m1A	2.04 ± 0.53	2.30 ± 0.62	2.74 ± 0.80a
I	0.28 ± 0.11	0.27 ± 0.11	0.50 ± 0.35a
m5U	0.04 ± 0.06	0.12 ± 0.06c	0.13 ± 0.08a
G	0.09 ± 0.03	0.08 ± 0.02	0.10 ± 0.04
m1I	1.25 ± 0.28	1.97 ± 0.50c	2.76 ± 1.94a
m1G	0.82 ± 0.24	1.21 ± 0.26c	1.44 ± 0.51a
ac4C	0.69 ± 0.20	0.70 ± 0.19	0.84 ± 0.30a
m2G	0.55 ± 0.14	0.52 ± 0.28	0.63 ± 0.26a
A	0.52 ± 0.16	0.59 ± 0.25	0.66 ± 0.30a
m22G	1.25 ± 0.23	1.43 ± 0.27	1.81 ± 0.55a
m6A	0.04 ± 0.02	0.06 ± 0.05	0.07 ± 0.05a

^aP < 0.05 patients with colorectal cancer vs healthy adults.

^cP < 0.05 patients with intestinal villous adenoma vs healthy adults.