Effects of dietary intake and genetic factors on hypermethylation of the hMLH1 gene promoter in gastric cancer

Table 2 Interaction between cigarette smoking and alcohol intake, and hMLH1 gene promoter hypermethylation in gastric cancer

	Controls	Cases without	Cases with	χ2trend
	(n)	hMLH1 promoter	hMLH1 promoter
		hypermethylation	hypermethylation
		(n)	(n)
Smoking history
Non-smoker	102	27	13	3.827
Smoker	117	42	24
Odds ratio	Referent (1.00)	1.16 (0.62 – 2.17)	3.04a (1.29 – 7.19)
Alcohol drinking
Never	95	26	15	1.327
Ever	124	43	22
Odds ratio	Referent (1.00)	1.07 (0.57 – 2.01)	2.11 (0.90 – 4.98)

Odds ratio was adjusted for age and sex.

^aP<0.05 vs others.