Different cell kinetic changes in rat stomach cancer after treatment with celecoxib or indomethacin: Implications on chemoprevention

Figure 3 Effects of celecoxib or indomethacin on the apoptosis index to proliferation ratio (AI/PI) of gastric tumors. The mean AI/PI ratio with standard error was shown. There was a significant difference in the AI/PI ratio among different treatment groups (P = 0.026, ANOVA). The highest ratio was seen in gastric tumors treated with celecoxib at 10 mg/(kg·d) whereas the lowest ratio was seen in tumors from MNNG group. The AI/PI ratio appeared to inversely correlate with the tumor incidence reported in different treatment groups (Table 1).