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World J Gastroenterol. Dec 14, 2021; 27(46): 7894-7908
Published online Dec 14, 2021. doi: 10.3748/wjg.v27.i46.7894
Hepatic pseudolesions caused by alterations in intrahepatic hemodynamics
Satoshi Kobayashi
Satoshi Kobayashi, Department of Quantum Medical Technology, Kanazawa University Graduate School of Medical Sciences, Kanazawa 9200942, Ishikawa, Japan
Author contributions: Kobayashi S designed and wrote the manuscript, and collected relevant data and approve the final manuscript.
Conflict-of-interest statement: The author declares that he has no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Satoshi Kobayashi, MD, PhD, Professor, Department of Quantum Medical Technology, Kanazawa University Graduate School of Medical Sciences, 5-11-80, Kodatsuno, Kanazawa 9200942, Ishikawa, Japan. satoshik@staff.kanazawa-u.ac.jp
Received: April 19, 2021
Peer-review started: April 19, 2021
First decision: June 23, 2021
Revised: June 23, 2021
Accepted: November 25, 2021
Article in press: November 25, 2021
Published online: December 14, 2021
Core Tip

Core Tip: Understanding the characteristics of hepatic blood flow and the pathophysiology of pseudolesions caused by alterations in intrahepatic hemodynamics is important for diagnostic imaging of liver lesions. The concept of hepatic arterial buffer response, a unique mechanism for regulating hepatic blood flow, might be essential for elucidating the pathogenesis of hepatic arterial-portal vein shunting and transient hepatic attenuation difference on dynamic contrast-enhanced imaging of the liver. In addition, some pseudolesions are associated with histopathologic changes such as focal hyperplasia, focal fatty liver, and focal sparing of fatty liver. Understanding these phenomena may aid in interpreting liver imaging findings.