Case Report
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Aug 7, 2021; 27(29): 4929-4938
Published online Aug 7, 2021. doi: 10.3748/wjg.v27.i29.4929
Autoimmune enteropathy and primary biliary cholangitis after proctocolectomy for ulcerative colitis: A case report and review of the literature
Qing-Yang Zhou, Wei-Xun Zhou, Xi-Yu Sun, Bin Wu, Wei-Yang Zheng, Yue Li, Jia-Ming Qian
Qing-Yang Zhou, Wei-Yang Zheng, Yue Li, Jia-Ming Qian, Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Wei-Xun Zhou, Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Xi-Yu Sun, Bin Wu, Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
Author contributions: Zhou QY drafted the manuscript; Zhou WX collected the pathological data and interpret the histological examination; Zhou QY, Zheng WY, and Li Y contributed to clinical data collection and follow up; Wu B and Sun XY performed the operation; Li Y and Qian JM critically revised the manuscript; all authors have read and approved the final manuscript.
Supported by Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (CIFMS), No. 2017-I2M-3-017.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report.
Conflict-of-interest statement: Dr. Li Y reports grants from Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences, during the conduct of the study.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yue Li, MD, Associate Professor, Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, No. 1 Shuaifuyuan, Dongcheng District, Beijing 100730, China. yuelee76@gmail.com
Received: February 25, 2021
Peer-review started: February 25, 2021
First decision: April 18, 2021
Revised: April 29, 2021
Accepted: July 13, 2021
Article in press: July 13, 2021
Published online: August 7, 2021
Core Tip

Core Tip: This is the first case report of autoimmune enteropathy and primary biliary cholangitis complicated with ulcerative colitis, and the female patient in this case suffered from a tortuous process of diagnosis and treatment. It is speculated that a microbial shift and subsequent immune response are involved in the pathogenesis of these comorbidities, and surgery may facilitate the progression of coexisting diseases. Understanding the progression of these diseases may help with their early recognition and treatment.