Published online Mar 7, 2016. doi: 10.3748/wjg.v22.i9.2828
Peer-review started: September 1, 2015
First decision: October 15, 2015
Revised: November 4, 2015
Accepted: November 24, 2015
Article in press: November 24, 2015
Published online: March 7, 2016
Core tip: Intra-abdominal bleeding, colonic fistula, and progressive infection are the three major early post-procedural complications in patients with acute necrotizing pancreatitis regardless of the selected approach. Possible predictors, accurate diagnosis, and appropriate management methods are beneficial to decrease the mortality rate and convalescence, as well as promote the life quality of patients with acute pancreatitis. In this study, Marshall score, organ failures, preoperative respiratory infection, sepsis, preoperative systemic inflammatory response syndrome, and C-reactive protein level upon admission are associated with post-procedural complications. Proper and gentle intervention process, and close monitoring and evaluation of patients who are prone to suffer from postoperative complications may increase the therapeutic efficiency.