Review
Copyright ©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Mar 7, 2016; 22(9): 2725-2735
Published online Mar 7, 2016. doi: 10.3748/wjg.v22.i9.2725
Liver surgery in cirrhosis and portal hypertension
Christina Hackl, Hans J Schlitt, Philipp Renner, Sven A Lang
Christina Hackl, Hans J Schlitt, Philipp Renner, Sven A Lang, Department of Surgery, University Medical Center Regensburg, 93053 Regensburg, Germany
Author contributions: Hackl C and Lang SA acquired the data and drafted the article; Hackl C, Schlitt HJ, Renner P and Lang SA contributed to conception and design, critical revision for important intellectual content; all authors approved the final version to be published.
Conflict-of-interest statement: Authors declare no conflict of interest for this article.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Christina Hackl, MD, Department of Surgery, University Medical Center Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany. christina.hackl@ukr.de
Telephone: +49-941-9446801 Fax: +49-941-9446802
Received: September 22, 2015
Peer-review started: September 23, 2015
First decision: October 14, 2015
Revised: November 1, 2015
Accepted: December 30, 2015
Article in press: December 30, 2015
Published online: March 7, 2016
Core Tip

Core tip: Liver resections in patients with underlying hepatic cirrhosis and portal hypertension still represent a medical challenge with regard to perioperative morbidity, surgical management and postoperative outcome. However, the increasing incidence of liver cirrhosis on the one hand, and the ongoing improvements in surgical technique and perioperative management on the other hand have up until today rendered even extended hepatic resections in these patients possible. Especially in primary and metastatic liver malignancies, surgery often presents the only curative approach and thus potential short- and long-term benefits and risks have to be evaluated carefully and interdisciplinary from a surgical, oncological and hepatologist point of view.