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World J Gastroenterol. Feb 7, 2014; 20(5): 1371-1376
Published online Feb 7, 2014. doi: 10.3748/wjg.v20.i5.1371
Published online Feb 7, 2014. doi: 10.3748/wjg.v20.i5.1371
Bowel mesentery (meso-appendix) microcystic/reticular schwannoma: Case report and literature review
Shao-Xian Tang, Jian Wang, Department of Pathology, Shanghai Cancer Center, Fudan University, Shanghai 200032, China
Shao-Xian Tang, Jian Wang, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Yi-Hua Sun, Xian-Rong Zhou, Department of Pathology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai 200011, China
Author contributions: Sun YH collected the data and pathological materials; Tang SX wrote the paper; and Zhou XR and Wang J proofread the paper.
Supported by National Key Clinical Specialty Project and Key Clinical Program of the Chinese Ministry of Health and the National Natural Science Foundation of China, No. 81272630
Correspondence to: Jian Wang, MD, PhD, Department of Pathology, Shanghai Cancer Center, Fudan University, No. 270, Dong An Road, Shanghai 200032, China. jwang@shca.org.cn
Telephone: +86-21-64176007 Fax: +86-21-64176007
Received: August 30, 2013
Revised: November 3, 2013
Accepted: December 5, 2013
Published online: February 7, 2014
Revised: November 3, 2013
Accepted: December 5, 2013
Published online: February 7, 2014
Core Tip
Core tip: Microcystic/reticular schwannoma is a recently described variant of schwannoma with a predilection for the gastrointestinal (GI) tract. The striking reticular growth pattern and myxoid background may cause confusion with several other tumors commonly seen in the GI tract, in particular a gastrointestinal stromal tumor with prominent myxoid change and a signet ring cell carcinoma, especially on small biopsies. Herein we report for the first time a microcystic/reticular schwannoma arising primarily in the meso-appendix to highlight its existence and enhance pathologist’s and clinician’s awareness of this under-recognized variant of schwannoma so as to avoid misdiagnosis and mistreatment.