Therapeutic options for the management of pancreatic cancer

doi:10.3748/wjg.v20.i32.11142

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Aug 28, 2014 (publication date) through May 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2014; 20(32): 11142-11159
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11142

Therapeutic options for the management of pancreatic cancer

Maria L Rossi, Azeem A Rehman, Christopher S Gondi

Maria L Rossi, Azeem A Rehman, Christopher S Gondi, Department of Medicine, University of Illinois College of Medicine-Peoria, Peoria, IL 61656-1649, United States

Author contributions: Rossi ML and Gondi CS provided the conception and design the article; Rossi ML, Rehman AA and Gondi CS drafted the article; Rossi ML and Gondi CS revised the critically important content, and provided the final approval of the version to be published.

Supported by Grant from the William E McElroy Foundation, Springfield, IL 62794-9264, United States to Gondi CS; and the Carrie M. Craig Medical Student Summer Research Fellowship Program sponsored by the University of Illinois College of Medicine at Peoria, Box 1649, Peoria, IL 61656-1649, United States to Rossi ML

Correspondence to: Christopher S Gondi, PhD, Assistant Professor, Department of Medicine, University of Illinois College of Medicine-Peoria, Box 1649, Peoria, IL 61656-1649, United States. gondi@uic.edu

Telephone: +1-309-4958167 Fax: +1-309-6557732

Received: October 25, 2013
Revised: January 11, 2014
Accepted: May 28, 2014
Published online: August 28, 2014

Core Tip

Core tip: Pancreatic ductal adenocarcinoma has challenged researchers for decades. It remains one of the most deadly cancers due to the complex molecular and genetic makeup of its cancer cells and their surrounding microenvironment. In addition, there are no valid screening tests available to detect pancreatic cancer in its early stages. Yet, as knowledge of this cancer has evolved over time, so have novel methods for treating it. Researchers have a deeper understanding of pancreatic cancer now than ever before. The future holds much promise for new breakthroughs that will significantly improve patient outcomes.