Natural history, treatment and prevention of hepatitis C recurrence after liver transplantation: Past, present and future

doi:10.3748/wjg.v20.i32.11069

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Aug 28, 2014 (publication date) through May 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Topic Highlight

World J Gastroenterol. Aug 28, 2014; 20(32): 11069-11079
Published online Aug 28, 2014. doi: 10.3748/wjg.v20.i32.11069

Natural history, treatment and prevention of hepatitis C recurrence after liver transplantation: Past, present and future

Jérôme Dumortier, Olivier Boillot, Jean-Yves Scoazec

Jérôme Dumortier, Olivier Boillot, Unité de Transplantation Hépatique-Fédération des Spécialités Digestives, HCL, Hôpital Edouard Herriot, 69437 Lyon, France

Jérôme Dumortier, Olivier Boillot, Jean-Yves Scoazec, Université Claude Bernard Lyon 1, 69437 Lyon, France

Jean-Yves Scoazec, Service d’Anatomie et Cytologie Pathologiques, HCL, Hôpital Edouard Herriot, 69437 Lyon, France

Correspondence to: Jérôme Dumortier, MD, PhD, Unité de Transplantation Hépatique-Fédération des Spécialités Digestives, HCL, Hôpital Edouard Herriot, Cedex 03, 69437 Lyon, France. jerome.dumortier@chu-lyon.fr

Telephone: +33-4-72110111 Fax: +33-4-72110147

Received: October 29, 2013
Revised: March 7, 2014
Accepted: June 20, 2014
Published online: August 28, 2014

Core Tip

Core tip: This paper reviews the evolution of our knowledge on the natural history of hepatitis C virus (HCV) recurrence after liver transplantation, including risk factors for disease progression, and antiviral therapy. It is necessary to define an innovative public health policy to improve HCV screening which is the only way of allowing non-tested HCV patients access to therapy before they develop advanced liver disease.