Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Jul 28, 2014; 20(28): 9299-9313
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9299
Published online Jul 28, 2014. doi: 10.3748/wjg.v20.i28.9299
Helicobacter pylori infection - recent developments in diagnosis
Ana Isabel Lopes, Centro Académico de Medicina de Lisboa, Faculdade de Medicina da Universidade de Lisboa, 749-016 Lisboa, Portugal
Filipa F Vale, Centro de Patogénese Molecular, Unidade dos Retrovírus e Infecções Associadas, Instituto de Medicina Molecular e Instituto de Investigação do Medicamento, Faculdade de Farmácia, Universidade de Lisboa, 1749-016 Lisboa, Portugal
Mónica Oleastro, Laboratório Nacional de Referência das Infeções Gastrintestinais, Departamento de Doenças Infeciosas, Instituto Nacional de Saúde Dr Ricardo Jorge, 749-016 Lisboa, Portugal
Author contributions: Lopes AI planned the paper’s general structure, format and content; all the authors contributed equally to the paper and its final revision.
Correspondence to: Ana Isabel Lopes, Professor, MD, PhD, Centro Académico de Medicina de Lisboa, Faculdade de Medicina da Universidade de Lisboa, Av. Professor Egas Moniz, Código Postal 1649-035 Lisboa, Portugal. anaisalopes@sapo.pt
Telephone: +351-217-805000 Fax: +351-217-548215
Received: November 9, 2013
Revised: February 28, 2014
Accepted: April 15, 2014
Published online: July 28, 2014
Revised: February 28, 2014
Accepted: April 15, 2014
Published online: July 28, 2014
Core Tip
Core tip: Considering the importance of a reliable diagnosis in the setting of current recommendations for Helicobacter pylori (H. pylori) eradication therapy, recent developments in both invasive and non-invasive methods may further contribute to improving H. pylori detection. The manuscript presents an extensive overview of the major advances in endoscopy, histology, culture, urea breath test, serology, stool tests and molecular methods, emphasizing their major contributions and potential shortcomings.