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World J Gastroenterol. Jun 21, 2014; 20(23): 7505-7513
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7505
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7505
Interferon-associated retinopathy risk in patients with diabetes and hypertensive hepatitis C
Ji-Hua Xue, Hai-Hong Zhu, Jing Wang, Zhi Chen, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, Zhejiang Province, China
Author contributions: Xue JH and Zhu HH designed the research; Xue JH and Wang J performed the searches and data collection; Zhu HH and Chen Z supervised the research; Xue JH and Chen Z analyzed the data; Xue JH and Wang J wrote the paper.
Supported by National Natural Science Foundation of China, No. 81201291; National Science and Technology Major Project, No.2012ZX10002003; and Science and Technology Major Projects of Zhejiang Province, No. 2009C03011-2
Correspondence to: Zhi Chen, PhD, MD, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Disease, the First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zju.zhichen@gmail.com
Telephone: +86-571-87236579 Fax: +86-571-87068731
Received: October 8, 2013
Revised: February 11, 2014
Accepted: March 4, 2014
Published online: June 21, 2014
Revised: February 11, 2014
Accepted: March 4, 2014
Published online: June 21, 2014
Core Tip
Core tip: This meta-analysis demonstrated that patients with hypertension were at higher risk for developing retinopathy when receiving interferon-based therapy for chronic hepatitis C infection. Further studies are needed to clarify the association between diabetes mellitus and interferon-associated retinopathy.